Propiophenone, CAS 93-55-0

Propiophenone is an organic compound often called ethyl phenyl ketone, benzoylethane, or BzEt. The IUPAC name of the substance is 1-phenylpropan-1-one. The molecular formula of the chemical is C9H10O; its CAS number is 93-55-0.


This compound is an aryl ketone. In propiophenone structure, two substituents on the carbonyl C atom are ethyl and phenyl.

The chemical is also characterized by the following properties:

  • Molar mass: 134.18 g·mol−1;
  • Density: 1.0087 g/mL;
  • Melting point: 18.6 °C;
  • Boiling point: 218 °C

The substance is liquid clear colorless to light amber tint with strong, persistent pleasant flowery odor. It is insoluble in water, ethylene, glycerol, and propylene glycol, but miscible with ether, benzene, anhyd ethanol, methanol, and toluene.

According to MSDS information, propiophenone is irritant, even its vapors can cause harm to eyes and respiratory system. Its fire potential is slight; the flash point is 87 °C. The substance can react with oxidizing materials.

Preparation and Application

The two most popular methods of propiophenone production are:

  1. Friedel-Crafts reaction of benzene and propionic acid chloride.
  2. Ketonization of propionic and benzoic acid over alumina and calcium acetate at 450-550 °C.

The chemical is mainly used as an intermediate in the synthesis of organic compounds and diverse pharmaceuticals.  It is often applied as flavoring agent in food industry. Due to the flowery aroma, the substance may serve as a component of some perfumes.

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